An easy route to synthetic analogues of radicamine B, codonopsine and codonopsinine from D-mannitol.
نویسندگان
چکیده
A general strategy for the synthesis of analogues of radicamine B has been carried out from D-mannitol. This method has been further extended to the synthesis of analogues of codonopsine and codonopsinine using appropriate Grignard reagents. The hence obtained molecules have been tested against various commercially available glycosidases and found to act as moderate to good inhibitors.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 27 شماره
صفحات -
تاریخ انتشار 2014